Pyruvate is a substance formed in the processing of carbohydrates and proteins that serves as an energy source for cells. It is a key intermediate in the glycolytic and pyruvate dehydrogenase pathways, which are involved in biological energy production. Pyruvate is widely found in living organisms. Pyruvate supplies the body with pyruvic acid, a natural compound that plays important roles in the manufacture and use of energy. Pyruvate supplements have become popular with bodybuilders and other athletes, based on claims that it can reduce body fat and enhance the ability to use energy efficiently.
Pyruvate is a biological fuel source. It may also have cardiac and skeletal muscle inotropic activity as well as bariatric activity. It also has antioxidant activity. It may help some obese individuals lose weight. Recent researches suggest that it might help some overweight individuals lower their blood pressure, and it may favorably modify lipid profiles. It also appears to enhance exercise endurance in some and may be protective in others with cardiac ischemia.
References:
PDR Health. http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/pyr_0218.shtml
Health Library. http://healthlibrary.epnet.com/GetContent.aspx?token=e0498803-7f62-4563-8d47-5fe33da65dd4&chunkiid=21633
