Vinpocetine is a semi-synthetic derivative of vincamine, which is extracted from the periwinkle plant. It increases cerebral blood flow and is said to improve memory. It is a powerful memory enhancer. It facilitates cerebral metabolism by improving cerebral microcirculation (blood flow), stepping up brain cell ATP production (ATP is the cellular energy molecule), and increasing utilization of glucose and oxygen.
Vinpocetine has several possible actions, including increasing cerebral blood flow and metabolism, anticonvulsant, cognition enhancement, neuroprotection and antioxidant. Vincamine, the parent compound of Vinpocetine, is believed to be a cerebral vasodilator. It is often used for the treatment of cerebral circulatory disorders such as memory problems, acute stroke, aphasia (loss of the power of expression), apraxia (inability to coordinate movements), motor disorders, dizziness and other cerebro-vestibular (inner-ear) problems, and headache. The primary claim made for Vinpocetine is that it decreases fatality and dependency in ischemic stroke. Research results are mixed. It may help with dementias and cerebral dysfunction. Very preliminary research additionally suggests that Vinpocetine may help protect the eye and ear from injuries caused by trauma (and, in the case of the eye, from infection) and that it might be gastroprotective, ameliorate symptoms of motion sickness and help prevent atherosclerosis. Vinpocetine exerts a brain neuroprotective effect by a combined action on cerebral circulation, brain metabolism, and rheological properties of the blood. Some preliminary research suggests that it may reduce some of the long-term cognitive impairment after an acute ischemic stroke — supposedly by improving blood flow to the brain.
References:
PDR Health. http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/vin_0259.shtml
MayoClinic.Com. http://www.mayoclinic.com/health/vinpocetine/AN01404
Smart Drugs & Nutrients, http://www.smart-publications.com/memory/vinpocetine.php
