Regular Retail: $39.95HYALURONIC ACID(HA), also known as hyaluronan, is an important disaccharide found in every tissue of the body, but in particular as an essential lubricant of healthy joints, skin and eyes. It is part of a group of macromolecules in the body labeled as glycosaminoglycans (GAGs), which are primarily in cell membranes and in the intercellular matrix of connective tissue. Along with water, HA's unique property of high viscosity, and therefore low compressibility, provides vital shock absorption and lubrication properties. In the intercellular matrix, HA essentially operates with water to "bathe" cells.
Glucosamine hydrochloride (GH) has been widely available as a dietary supplement for years, but only one trial has evaluated this form of glucosamine as a single remedy for OA.3 This trial found only minor significant benefits from 1,500 mg per day of GH for eight weeks, in people with osteoarthritis of the knee who were also taking up to 4,000 mg/day of acetaminophen. To more fairly evaluate the effects of GH, future research should involve people not taking pain-relieving medication.
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