Magnolia bark (Magnolia officinalis) is a traditional Chinese medicine used since 100 A.D. to support the body and nurture wellbeing and to treat a plethora of ailments. Magnolia bark has been used to treat menstrual cramps, abdominal pain, abdominal bloating and gas, nausea, and indigestion. The bark is also an ingredient in formulas used for treating coughs and asthma. The bark is used internally in the treatment of abdominal distension, loss of appetite, gastro-enteritis, vomiting, diarrhoea, asthma and coughs with acute phlegm. Magnolia bark is rich in two biphenol compounds, (magnolol and honokiol), which are thought to contribute to the primary anti-stress and cortisol-lowering effects of the plant.
Magnolol was found in studies to support the body's natural production of adrenal steroids (corticosteroids) which suppress inflammation. This anti-inflammatory effect is thought responsible for alleviating the allergic inflammatory response in cases of asthma. It has several powerful effects on acetylcholine levels in the brain, offering potential benefits for victims of Alzheimer's Disease. Alzeimer's Disease is characterised by insufficient levels of acetylcholine, accompanied by the buildup of amyloid plaque in the brain, disrupting normal brain functioning. Honokiol and magnolol, increase choline acetyltransferase activity, inhibit acetylcholinesterase, promote potassium-induced acetylcholine release and exhibit neurotrophic function in in vitro studies. Magnolia bark is used as a general anti-stress and anti-anxiety agent - so its claims typically center on general benefits in controlling stress and anxiety.
References:
http://www.herbwisdom.com/herb-magnolia.html
http://www.fitfaq.com/magnolia-bark.html