Inosine is a nucleoside, one of the basic compounds comprising cells, used for tiredness and to increase athletic performance. It is a precursor to adenosine, an important energy molecule, and plays many supportive roles in the body, including releasing insulin, facilitating the use of carbohydrate by the heart, and, potentially, participating in oxygen metabolism and protein synthesis. It is associated with the development of purines, nonprotein nitrogen compounds that have important roles in energy metabolism. It has been suggested that Inosine may improve ATP (Adenosine Tri-Phosphate) production in the muscle and thus be of value to strength athletes. It is also thought to enhance oxygen delivery to the muscles which would benefit endurance athletes. It may have neuroprotective, cardioprotective, anti-inflammatory and immunomodulatory activities. There is some preliminary evidence that Inosine may have some neurorestorative, anti-inflammatory, immunomodulatory and cardioprotective effects. Inosine is used to treat viral infections such as genital herpes and genital warts.
Inosine supplements have been used as an energy-booster for athletes, as well as a treatment for various heart conditions. It is a metabolic activator. It has been used for pre-heavy training by world class power-lifters and athletes to increase oxygen-carrying capacity and promote levels of ATP a high energy compound that helps muscle contraction. Inosine increases the body's natural ability to handle strenuous exercise, workouts, intense training programs, and competitive events. It belongs to a chemical family called purine nucleotides, the structural units of your body's RNA (ribonucleic acid) and DNA (deoxyribonucleic acid). Inosine easily penetrates the cell walls of both your cardiac and skeletal muscles there inosine helps the generation of ATP. It boosts the production of ATP thus improving respiration and oxygen transport.
References:
PDR Health. http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/ino_0144.shtml
http://www.patient.co.uk/showdoc/30003245/
http://healthlibrary.epnet.com/GetContent.aspx?token=e0498803-7f62-4563-8d47-5fe33da65dd4&chunkiid=21764
http://www.bodyandfitness.com/Information/Fitness/Research/inosine.htm
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